You're not more likely to miss a spell with a mastery proc than an int/haste proc, that's not what I said, but if you miss a spell that would otherwise extend your proc, that's a big deal. You can extend the mastery proc by casting MB just as it ends, and extend it further by re-casting VT and DP as the Empowered Shadow buff is ending. Effectively you can extend a mastery proc twice, for example with Theralion's Mirror you can get (on average) 55 seconds of mastery-proc buffed DP every 112 seconds, but you lose 24 seconds of that if the DP that you cast at the end of the ES buff misses.