Hehe yeah, I'm not sure we're on the same page But what I've described works with Clique, and you can't do it without Clique or a similar addon (same with the left mouse button). One thing to realize is that clique works in frames, as opposed to models in the 3d-World (i.e. what you'll not be able to do is decursing on right-mousebutton on the unit of the 3d-model you're hovering your mouse over).
If you want to use other mouse buttons, that's possible without Clique indeed, and also Clique doesn't give you any new modifiers or such to use in macros. Is that what you're meaning?