He was talking about mouse-over macros, that's why I was suggesting focus macros. They're more time efficient than clicking in addition to freeing up your mouse for movement.I know there I can make a macro where I would need to click a button while mouse-over the enemy
This is one of the better ways to do it imo, depending on spell (don't go overboard on it). Though I would still suggest having a focus macro created for things such as RBGs.