Never been a real fan of doing rep grinds and dailies in any of the WoW releases. Haven't touched them at all this expansion and I plan to keep it that way (aside from maybe the Cloud Serpent ones, I thought they were fun in beta).
Uhmmm... I was playing Ninja Gaiden way back and got stuck at a particular part where I had super low health, only several things to kill right before the boss (for a chance to get some health back) and the boss was severely difficult to avoid taking damage from. I ended up quitting the game because I refused to restart the whole adventure over again and could not defeat the boss with that amount of health.