Originally Posted by
Reniat
4) Playstyle
Single Target:
Use FU runes (including combos of F U and D runes) on Death strike, dump Runic Power with Rune Strike, make sure you always have diseases on targets you are tanking, and dump blood runes with heart strike (above 35%) Soul Reaper (below 35%) and make sure you are keeping diseases up through Blood Boils from Crimson Scourge to refresh them. If you are left with an open GCD, use Horn of Winter. It's free Runic Power and should be used anytime you don't have something else to use.