They have yet to make fun of Reddit, but they pretty much go after the most absurd shit that people are complaining about. They have been ripping on Trump through Mr Garrison for 3 seasons now, they ripped on Bruce Jenner running someone over, PC culture, SJW's, recently they made fun of white people who renovate houses on TV, BLM last season in an episode called Token's Life Matters. Doesn't matter which side of the coin you are on, you are a target.
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Some of the stuff that is considered PC today was PC 30 years ago. George Carlin would be doing 3 shows a day if he were still alive because so much of the shit today can easily be spun into comedy.
"I'll see you so...wait! What the fuck that's supposed to mean"
lol, this made my day