The biggest problem with Monkeypox is that most US doctors are not familiar with the disease.
NPR did an interview with a Bay Area man that had Monkey Pox. He was bounced around between doctors, hospitals and emergency rooms. Until he finally drove himself to UCSF. Dr. Peter V. Chin-Hong, an epidemiologist at UCSF, saw him, did not wait for test results, and prescribed oxycodone for the pain & TPOXX. Which took care of the problem almost immediately. Here is the interview.