Too many NPCs to make a poll, really.
Soooo I have two. First is the farmer granny with the shotgun in Bradenbrook, who I can't really remember the name of. Shoulda called her Grandma: 76.
And second is Margaux, the lady Vintner in the vineyards. She sounded so cheerful and happy and stuff, and her line delivery was amazing. And then she died. I then proceeded to go on a 30 minute killing spree, because I was a sad pala. =I