GW1 didn't allow the use of modifiers and from this video,
http://www.youtube.com/watch?v=cEXbd...=youtu.be&hd=1
it specifically states that "Keys couldn't be rebound to CTRL + or Shift + leaving some mouse clicking necessary". And from the video posted above by Fencers, they never said anything about modifiers. The player could have been using a Naga, which GW1 did allow the use of assigning mouse buttons for keybinds. It's something simple that shouldn't be left out in a modern day MMO. Not having them in GW1 was a huge letdown for me and it's something that I never understood. They put default hotkeys as the Function keys. This was partly because GW1 was based around click-to-move movement, but this game is all about WASD type movement. Fix it ANet, plain and simple. It's not that hard and would please a lot of gamers.