Originally Posted by
Shakadam
Hmm if it's still the same even when hooked up to another computer it would seem that the likely problem is somewhere between the sound card and speakers, so yeah a ground loop isolator might work. I don't really have any experience with those but there are like millions of different ones, I'd advice going to a specialty audio store of some kind and ask for assistance, otherwise you can probably find ground loop isolators on for example, amazon.
EDIT: Are both computers you tried it in connected to a grounded power outlet?