Read this carefully. It has a nice sum up and its in English:
http://www.ausairpower.net/APA-Grumble-Gargoyle.html
TL;DR: Nothing penetrates the perimeter of S-300. Best chances has a F-22. Euro-fighter, f15, typhoon etc are all getting shot down.
If S-300 is combined with pantsir-S1 and TOR A/A systems they create basically a non penetrable A/A region aka FULL NO FLY ZONE FOR ALL PLANES. Note also that the article doesn't not include the recent (state of the art) L-BAND mobile Radars (anti F-22). Its gg if they want it
I highly doubt such infrastructure exists in Syria (other maybe than the Russian air base).