The situation where Unholy can make huge use of it is any close proximity add fight. Thinking the first set of adds on Garrosh. With Unholy Blight you would have a 15 stack up very fast, and when the adds come, you can pestilence and spread that, or just let it stack itself. As long as you maintain a 15 stacker on one mob, as long as it's in range of other adds, you'll have maximum damage bouncing around.
Shouldn't be THAT difficult to maintain it on one mob i guess.