I don't really know what I am looking for at this point. I love defense style games, loved Orcs must Die! but no matter what it seems I am always looking for more.
I am a big fan of Terraria and open world games where I can essentially shape the world around me. I love creating traps to defend against hordes of enemies while I pick off stragglers but that can get old sometimes since a simple lava trap can take out most anything.
I recently started playing a new game called Craft the World which is a mix of both Terraria and Dwarf!? I am really enjoying right now but even with the speed up function it can still take forever to do anything at all.
There are two tower defense traps in the game which are great when combined with fences and spike traps to slow down the zombies at night while you keep your Dwarves safe in base or set them to attack while mining for resources underground to upgrade their gear. I love those aspects of the game but sadly the game just feels too slow sometimes.
You may want to look into a game called Deathtrap. It is currently Early Access but it is made by the same people who created The Incredible Adventures of Van Helsing (which is an excellent ARPG) and has a great deal of potential.