Originally Posted by
Shaley
OP: We would need to see your armory. How -much- mastery and crit is an important question that needs answered. Some people with the triple Vendetta relic set up prefer Exsang. due to how it lines up with Vendetta. With 3 relics, or 2+Boots, your V+Exsang should line up 100% of the time, which is a good damage increase.
Something to keep in mind as well. If you go to WacraftLogs, you can sort individual bosses for US-Assassin Rogues and see what Talents the top 200, 400, or however deep you want to look, use. You'll see a large, large majority use Agonizing Poison for every fight. Ilgy, if you stay Assassination instead of going Outlaw, I believe is mainly Exsang due to many lower HP adds with burst windows. I haven't checked in a while, but don't forsee that changing.
As far as Nighthold goes, I haven't done enough prep on it yet. I know the Tier Bonus favors --Exsang-- (old data, perhaps. Don't know how much the incoming Exsang nerf alters this)., but I am not sure if it favors it enough to completely drop Agonizing Poison once you obtain the Tier bonuses.