As someone who loves gnomes but finds druids boring, I can't say I'm especially invested in the idea of this combo. Not because its ridiculous or violates some holy-grail lore thing, because gnomes could easily invent things to provide most if not all of the advantages of a druid. The 'D.R.U.I.D.' thing makes a strong case for that.
But even if they were a thing, I'd not likely play one because I just don't enjoy the mechanics of most druid specs.
I'd much rather see gnome paladins, personally.