Originally Posted by
styopa
If you have fans pushing air into the case, so you have higher pressure in the case ("positive" pressure), those fans are taking the air from somewhere, ie the world, ie air full of dust.
If you have fans pushing air out of the case, so you have a slightly lower pressure in the case, air is going to infiltrate the case through every crevice in the case, pulling in dust with it.
Either way, the difference is trivial.
That said, all else being equal, positive pressure is probably marginally better.
1) you can control where air is coming in; you can put filters over these specific points and make sure minimal dust is infiltrating into your case.
2) The best insulator in the world is a vacuum. Ergo, reducing the air pressure in your case moves it *marginally* toward a vacuum, ie lower efficiency in heat transfer away from your cooling vanes, etc. It's probably even below the level of being able to be measured, but my bet is that a case with lower pressure inside is going to shed head slightly less well.
In my case, however, I use negative pressure. Why? Because of airflow. Positive pressure fans blow air in a pattern into your case, causing eventually a stable pattern of air currents. This means certain areas get cooled better than others. Certainly, convection of the air will somewhat disrupt this, but generally a hot case will stabilize with certain airflow patterns. I can't afford that. Everything in my case runs hot, so I need airflow from all directions. Having negative pressure both causes airflow in from multiple directions, it is less likely to stabilize in a pattern. I get marginally better cooling with negative than positive.