I'm on a relatively high-end computer and my computer sometimes freezes up in combat, almost always in LFR or on world bosses. It seems everyone agrees that its main cause is recount churning all the numbers of everyone's damage and healing this expansion (Stampede making it even worse, partially due to a glitch). With 40+ man world bosses and bigger numbers, this was the biggest issue right at launch, before Recount optimized its routines, if you guys remember that. Recount is better optimized now and whatnot. However, as damage and healing gets bigger, it will keep getting slightly worse.
Eventually, the average person will not have a processor powerful enough to run a real-time DPS/HPS logger like Recount.
Thus, I am for an item squish whenever Blizzard feels it is appropriate. If it means I freeze up less? Definitely.