Yes I had a thread already and that got one reply saying it probably doesn't work and a link to a thread with info I already tried.
This thread I'm gonna add a little more info.
So I made a post on the GW2 forums and that got no where. I know I can use it in this game. People use other gaming mice, including the WoW cata. But I'm having an issue where only 3 binds work. One activates f1, another 'B', and the last one 'M'. So I know it works. When I close down the two programs for the mouse in task manager called "WoWMHID2" and "WoWMTray2" the keybinds deactivate and I can no longer save my mouse to on-board memory. I know I am binding the mouse correctly; I can type in the chat with the bound keys, like a bind for 'A' will type 'A' in the chat. I'm honestly not sure what is going on. I was able to bind these buttons with ease in SW:TOR but this game is being a huge bitch about it.