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Witchblade77 Just wanted to update on how I was doing to give you an idea of what to expect.
My new character is now level 24 and I'm doing the area of the map to the far SE, which is lvl 18-20. I actually still die pretty easily if I'm not careful, despite being 4 levels above the enemies. Although my gear is just whatever I find. I'm not using any crafted or vendor stuff, so you'll be better off in that regard.
Toughest enemies to solo are the heavy armored LMG guys. But with someone to flank for you they're probably a cakewalk.
All in all the worst part so far is occasionally walking back to where I died. I highly recommend using as many Dark Zone and mission entrances as waypoints that you can get to. Just using the safehouses is not enough.