I actually think Philly's offense matches up pretty well with the 49er's defense. They have a dominant offensive line and will probably be able to run directly at Bosa to slow him down as a pass rusher, which is going to open things up in the passing game. Philly might be a run-first team, but they are also fully capable in the passing game, and Hurts does a really good job of taking care of the football. I think the 49ers will struggle against a team as balanced offensively as Philly is.