Originally Posted by
SSHA778
Increasing the number of Death Strikes you use per minute is massive in terms of overall damage reduction. Just using 1 more per minute from 8, which is simple enough with exploiting BT, has the same effect as adding (estimated) ~500-800 total rating in the current region we're in. I would need to run more iterations to isolate that further, but I think the point gets across. Doing 1 more than that (so 10/min) isn't another ~500-800 all the time (decreases as you increase #DS), but it's a pretty significant deal. It's less for avoidance since mastery isn't as large of a factor. The effect on CTC is larger for both sets. Again, that's not the same as overall damage reduction. This is also another reason why you should, if at all possible, let your offtank put up tank debuffs for you.
If anything, the bleeding optimization is by far the most important in your rotation. Anything else pales in comparison.