Since deadly brew also applies other poisons, I would benefit from both the burst damage of having 2 instant poisons and deadly poison would always be up as well, which boosts mutilate damage by 50%, in addition to the 20% mutilate damage boost from opportunity in subtlety, along with a 30% mutilate crit damage boost from lethality. As far as upping the crit chances itself, you get a 26% passive critical hit chance boost for mutilate (assuming that someone, somewhere in your raid happens to dodge, block, or parry which is..likely.), and assuming the mobs are more than just one enemy, relentless strikes can help up the next mutilate crit chance to 66% which isn't bad, and killing an enemy in a raid isn't something out of the ordinary. As well, the instant poisons and deadly poisons get a 40% damage boost total from vile poisons and infectious poisons. I've played mutilate for a long time, I don't care if someone is like "noob roll combat swords its the only way kthnxbye". Let's try and keep it a discussion and not an argument.