How is it prominent? It's like half assed mentioned in a conversation string that most people would of missed if every wow news site and click bait YouTuber didn't make a big deal about it.
It's literally never mentioned again, he doesn't even go by a "they" pronoun, no point in the game does he try to correct people on his gender nor is it ever questioned.
Fuck Poison from Street Fighter being trans is more prominent and it's literally NEVER mentioned