Can't screenshot it right now, but I was questing in Zangamarsh. Was about to accept all the quests around the first area when I missclicked one. I clicked the "ignore" button on the bottem right corner. That's where the Goodbye button usually was. It then said "This quest is now ignored. If you want to accept it, you have to interact with the questgiver again."
When I talked to him it showed me the quest as usual, but with an "(ignored)" behind it.