Pardon, been about a year since I played. How did I think SB was off the GCD? Anyway... same thing, just blank out the GCD stuff.
Right, I agree, if you are dying because of focusing too much on the clicking, there's a problem. For me though and surely many others, it feels like second nature. It helps that you would usually plan out in advance when you need to be hitting that Shield Wall/any other big CD. If you are playing something with a lot of reactionary cooldowns (let's say a paladin), then keybinds will surely massive improve your play.
One of my proudest moments was killing Kruul in the Mage Tower challenge shortly after it was released(2nd time the tower was up I believe), and I did it playing like this. That's really the highest praise I can give myself